TABLE 1.
Baseline and Procedural Characteristics of Patients in the Randomized PLATINUM Trial and the SV and LL Substudies
| Randomized CoCr-EES (n = 762) |
Randomized PtCr-EES (n = 768) |
SV Study (n = 94) |
LL Study (n = 102) |
|
|---|---|---|---|---|
| Patient characteristics | ||||
| Age, yrs | 63.1 ± 10.3 | 64.0 ± 10.3 | 64.33 ± 11.03 | 65.94 ± 9.79 |
| Male | 542 (71.1) | 550 (71.6) | 68 (72.3) | 64 (62.7) |
| Caucasian | 644 (84.5) | 650 (84.6) | 80 (85.1) | 83 (81.4) |
| Hypertension* | 558 (73.2) | 544/767 (70.9) | 75 (79.8) | 84 (82.4) |
| Hyperlipidemia* | 579/760 (76.2) | 598/765 (78.2) | 77 (81.9) | 84 (82.4) |
| Diabetes* | 191 (25.1) | 169 (22.0) | 40 (42.6) | 30/100 (30.0) |
| Smoking, ever | 448/741 (60.5) | 493/751 (65.6) | 59 (62.8) | 64/100 (64.0) |
| Prior myocardial infarction | 160/760 (21.1) | 160/761 (21.0) | 28 (29.8) | 34 (33.3) |
| Unstable angina | 188 (24.7) | 185/767 (24.1) | 23 (24.5) | 24/101 (23.8) |
|
| ||||
| Number of target lesions | ||||
| 1 | 684 (89.8) | 683 (88.9) | 94 (100) | 102 (100) |
| 2 | 77 (10.1) | 85 (11.1) | 0 | 0 |
|
| ||||
| Target lesion characteristics | ||||
| Reference vessel diameter, mm | 2.63 ± 0.49 | 2.67 ± 0.49 | 2.04 ± 0.26 | 2.56 ± 0.40 |
| Minimum lumen diameter, mm | 0.74 ± 0.34 | 0.75 ± 0.35 | 0.51 ± 0.21 | 0.73 ± 0.30 |
| Diameter stenosis, mm | 71.9 ± 11.5 | 71.8 ± 11.5 | 75.1 ± 9.5 | 71.7 ± 10.96 |
| Lesion length, mm | 12.5 ± 5.5 | 13.0 ± 5.7 | 14.15 ± 7.03 | 24.38 ± 8.21 |
|
| ||||
| Target vessel | ||||
| Left anterior descending | 343/813 (42.2) | 347/824 (42.1) | 32 (34.0) | 44 (43.1) |
| Left circumflex | 216/813 (26.6) | 217/824 (26.3) | 41 (43.6) | 22 (21.6) |
| Right | 254/813 (31.2) | 260/824 (31.6) | 21 (22.3) | 36 (35.3) |
|
| ||||
| Procedure characteristics | ||||
| No. of stents per patient | 1.20 ± 0.48 | 1.16 ± 0.44 | 1.00 ± 0.29 | 1.13 ± 0.36 |
| Total stent length per lesion, mm | 19.7 ± 8.9 | 20.5 ± 7.0 | 20.13 ± 7.38 | 37.51 ± 8.49 |
| Maximum dilation pressure, atm | 15.9 ± 3.2 | 16.3 ± 3.1 | 16.03 ± 3.39 | 17.50 ± 3.03 |
Values are mean ± SD, n (%), or n/N (%).
*
Requiring medication.
CoCr-EES = cobalt chromium everolimus-eluting stent(s); LL = long lesion; PLATINUM = PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions; PtCr-EES = platinum-chromium everolimus-eluting stent(s); SV = small vessel.