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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Alzheimers Dement. 2017 Oct 19;14(3):318–329. doi: 10.1016/j.jalz.2017.09.011

Table 2.

Correlations between brain tissue glucose concentration, brain tissue ratios of glycolytic amino acids:glucose, protein levels of the neuronal (GLUT3) and astrocytic (GLUT1) glucose transporters and AD pathology (Braak and CERAD scores)

rho P value Brain tissue glucose concentration Serine+glycine:glucose (Hexokinase_and Phosphofructokinase activities) Serine+glycine+alanine :glucose (Pyruvate kinase activity) protein levels of glucose transporters (MFG)
ITG MFG CB ITG MFG CB ITG MFG CB GLUT3 GLUT1
Braak 0.37
0.014
0.12
0.44
0.21
0.24
−0.37
0.016
−0.13
0.41
−0.22
0.23
−0.46
0.0093
−0.14
0.46
−0.22
0.22
−0.40
0.0051
0.038
0.80
CERAD 0.47
0.0014
0.39
0.0096
0.25
0.16
−0.52
0.0004
−0.38
0.013
−0.25
0.17
−0.55
0.0010
−0.31
0.087
−0.24
0.18
−0.42
0.0033
−0.21
0.16

ITG = inferior temporal gyrus; MFG = middle frontal gyrus; CB = cerebellum The numbers in each cell show the unadjusted Spearman’s rank correlation rho and corresponding p values.