Table 2.

Body weight, degree of stenosis, mean arterial pressure, renal vascular resistance, and renal cortical and medullary volumes (mean ± SEM) in normal, RVD, and RVD pigs before treatment (6 weeks after induction of RVD or sham operation) and four weeks after saline or ELP-VEGF treatment (10 weeks) (n=6–7 per group).

Parameter	Normal	RVD	RVD+ELP-VEGF
Pre-treatment values (6 weeks)
Body weight (kg)	43.2±3.8	45.1±2.1	46.6±2.8
Degree of stenosis (%)	0.0±0.0	75.1±7.2*	73.7±9.3*
MAP (mm/Hg)	96.0±2.4	139.1±9.3*	142.5±10.3*
RVR (mmHg/mL/min)	0.21±0.02	0.58±0.04*	0.64±0.05*
Cortical volume (cc)	117.8±7.0	60.4±6.3*	61.8±7.2*
Medullary volume (cc)	34.0±5.3	17.4±2.0*	18.1±1.9*
Post-Treatment values (10 weeks)
Body weight (kg)	51.3±5.2	54.2±2.9	54.5±2.8
Degree of stenosis (%)	0.0±0.0	74.9±6.5*	75.2±8.7*
MAP (mm/Hg)	100.1±1.9	150.4±10.4*	142.4±3.8*
RVR (mmHg/mL/min)	0.19±0.01	0.56±0.07*	0.47±0.06* †
Cortical volume (cc)	96.3±6.3	64.3±8.7*	64.2±5.9*
Medullary volume (cc)	31.1±6.5	18.4±2.1*	21.2±7.0*

^*p<0.05 vs. Normal;

^†p<0.05 vs. RVD.

MAP: mean arterial pressure, RVR: renal vascular resistance