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. Author manuscript; available in PMC: 2018 Aug 19.
Published in final edited form as: Nat Ecol Evol. 2018 Feb 19;2(4):705–712. doi: 10.1038/s41559-018-0471-0

Fig. 6. Art knockouts disrupt actin networks required for egg elongation.

Fig. 6

a, A pair of D. melanogaster ovaries, which are comprised of ovarioles and, b, developing egg chambers. c, Cross section of an egg chamber. BM: basement membrane. d,e, Follicle cell migration produces ordered basal actin structures that restrict egg girth during development to produce elongate mature eggs. f,g, Artnull females produce round eggs due to disruption of basal actin structures. We found no defects in border cell migration, ring canal formation, or nurse cell dumping that might otherwise explain the shape defect (Supplementary Fig. 6). Scale: d,f: 300 µm; e,g: 10 µm. h, Means and 95% CIs of egg lengths and volumes. Welch’s t-test *p < 0.05; **p < 0.01, ***p <0.001 compared to wild-type Artcontrol. Full statistical test results are shown in Supplementary Table 9.