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. Author manuscript; available in PMC: 2018 Aug 19.
Published in final edited form as: Nat Ecol Evol. 2018 Feb 19;2(4):713–720. doi: 10.1038/s41559-018-0478-6

Fig 5. Signatures of positive selection at the GYP locus on chromosome 4.

Fig 5

We observed signatures of positive selection in 13 populations at the GYP locus, including at least one population from each studied continental group. The top panel shows the sweep intervals of populations with sweeps at this locus, and the positions of the GYP genes. The bottom panels show the sweeping haplotypes for two African (ESN, GWD) and two South Asian (ITU, PJL) populations’ within-continent shared sweeps. The gray tick marks in each populations’ row indicate the presence of a derived allele on the sweeping haplotype most common in that population, with a black tick indicating the position of each population’s SNP with the most extreme iHS value. Also shown in orange are the significant eQTLs for GYPE (light orange) or both GYPB and GYPE (dark orange) in LD with these population’s shared haplotype (D’ = 1). The eQTLs for GYPB and GYPE are from whole blood.