. 2016 Oct 18;80(1):61–67. doi: 10.1007/s12262-016-1558-y

Table 2.

Sensitivity and specificity of white blood cell count, C-reactive protein level, lymphocyte count, neutrophil percentage, lymphocyte percentage, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio cutoff values to diagnose acute appendicitis

Cutoff	+ Appendectomy	− Appendectomy	AUC ± SE	p Value
WBC (K/μL)
WBC >11.3	367 (92.4) (65)^a	30 (7.6)^c (40)	0.663 ± 0.034	<0.001
WBC ≤11.3	198 (81.5)^d (35)	45 (18.5) (60)^b	0.663 ± 0.034	<0.001
Neutrophil percentage
Neutrophil percentage >74.9	422 (96.6) (74.7)^a	15 (3.4) (20)^c	0.755 ± 0.03	<0.001
Neutrophil percentage ≤74.9	143 (70.4)^d (25.3)	60 (29.6) (80)^b	0.755 ± 0.03	<0.001
Lymphocyte count (K/μL)
Lymphocyte count ≤1.76	368 (92.7) (65.1)^a	29 (7.3) (38.7)^c	0.628 ± 0.033	<0.001
Lymphocyte count >1.76	197 (81.1)^d (34.9)	46 (18.9) (61.3)^b	0.628 ± 0.033	<0.001
Lymphocyte percentage
Lymphocyte percentage ≤16.2	410 (96.9) (72.6)^a	13 (3.1) (17.3)^c	0.752 ± 0.03	<0.001
Lymphocyte percentage >16.2	155 (71.4)^d (27.4)	62 (28.6) (82.7)^b	0.752 ± 0.03	<0.001
CRP (mg/L)
CRP >51	212 (95.5) (37.5)^a	10 (4.5) (13.3)^c	0.621 ± 0.033	<0.001
CRP ≤51	353 (84.4)^d (62.5)	65 (15.6) (86.7)^b	0.621 ± 0.033	<0.001
NLR
NLR >4.64	411 (96.9) (72.7)^a	13 (3.1) (17.3)^c	0.752 ± 0.03	<0.001
NLR ≤4.64	154 (71.3)^d (27.3)	62 (28.7) (82.7)^b	0.752 ± 0.03	<0.001
PLR
PLR >126.44	400 (91.1) (70.8)^a	39 (8.9) (52)^c	0.588 ± 0.037	0.018
PLR ≤126.44	165 (82.1)^d (29.2)	36 (17.9) (48)^b	0.588 ± 0.037	0.018

Receiver operating characteristic curve analysis (Hanley and McNeil method, Youden index J)

^aSensitivity

^bSpecificity

^cFalse-positive ratio

^dFalse-negative ratio