Table 3.
Overview of studies from literature used to evaluate PBK model predictions
| Compound | Species (strain) | Sex | Dose (mg/kg bw) | Exposure route | References |
|---|---|---|---|---|---|
| E2 | Rat (Sprague–Dawley rats) | Male | 0.02, 0.04, 0.08 | Intravenous, oral | Bawarshi-Nassar et al. (1989) |
| E2 | Rat (Sprague–Dawley rats) | Female | 0.0056 | Intravenous | Larner and Hochberg (1985) |
| E2 | Rat (Sprague–Dawley rats) | Female | 0.01, 0.1 | Intravenous | Eisenfeld (1967) |
| BPA | Rat (Fisher 344) | Male | 10, 100 | Oral | Pottenger et al. (2000) |
| BPA | Rat (DA/Han rats) | Female | 10 | Intravenous | Upmeier et al. (2000) |