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. 2017 Dec 12;92(3):1075–1088. doi: 10.1007/s00204-017-2140-5

Table 4.

C max of E2 and BPA obtained from in vivo data and predicted by the PBK model in rats upon oral administration

Compound Dose (mg/kg bw) In vivo C max (µM) Predicted C max (µM) Predicted C max/in vivo C max References
E2 0.02 0.0006 0.0025 4.17 Bawarshi-Nassar et al. (1989)
E2 0.08 0.0027 0.0098 3.63 Bawarshi-Nassar et al. (1989)
BPA 10 0.1748 0.5833 3.34 Pottenger et al. (2000)
BPA 100 9.8774 5.8334 0.59 Pottenger et al. (2000)