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. 2017 Nov 15;11(2):100–102. doi: 10.1111/cts.12521

Figure 1.

Figure 1

Mechanism of aminoglycoside‐induced cytotoxicity in proximal tubule epithelial cells, and proposed mechanism for inhibition by statins. Adapted from Biochemical Pharmacology, Antoine, D.J. et al. Statins inhibit aminoglycoside accumulation and cytotoxicity to renal proximal tubule cells, 79, 647–654, ©2010, with permission from Elsevier.