Table 1.
TSP‐1 secretion rates from different cancer and non‐cancer cell types
| Human cell type (cell line) | TSP‐1 protein secretion rate (ng/106 cells/24 h) | References |
|---|---|---|
| Pancreatic cancer (AsPC‐1; Colo‐357; Panc‐1; T3M4) | 276; 61; 90; 94 | 44 |
| Glioma (T98G; U251; A172; KG‐1‐C; TM2; YMG1; YMG2; YMG3; YMG4; YMG5) | 2431; 275; 59; 43; 475; 69; 1081; 1450; 126; 250 | 45 |
| Breast cancer (YMB‐1) | 3 | 45 |
| Breast cancer (T47D; BT‐474)a | 3; 3 | 46 |
| Lung cancer (A549) | 20 | 45 |
| Gastric cancer (NUGC‐4) | 31 | 45 |
| Hepatic cancer (HLF) | 89 | 45 |
| Colon cancer (Colo‐201) | 3 | 45 |
| Prostate cancer (PC3) | 610 | 45 |
| Melanoma (DFB) | 8 | 45 |
| Neuroblastoma (IMR‐32) | 4 | 45 |
| B‐Chronic lymphocytic leukaemia (B cells from patients) | 9 | 47 |
| Promyelocytic leukaemia (NB4; HL‐60)b | 55; 40 | 48 |
| Kaposi's sarcoma (IST‐KS XVI; IST‐KS VIII; IST‐KS XI; IST‐KS IV) | 6500; 3400; 4400; 8500 | 51 |
| Human foreskin fibroblast | 474 | 44 |
| Human foreskin fibroblastc | 15 700 | 49 |
| Human foreskin fibroblastc | 3333 | 50 |
| Human foetal lung fibroblast (GM1604)c | 5800 | 49 |
| Endothelial cell (HUVEC)c | 21 000 | 49 |
| Endothelial cell (HUVEC) | 19 500 | 51 |
| Endothelial cell (HUVEC)c | 49 000 | 52 |
| Human aortic smooth muscle cellc | 9467 | 50 |
| Human dendritic celld | 10 153; 3053 | 53 |
| Human retinal glial cell (MIO‐M1) | 125 | 54 |
a
Unit conversion is implemented by assuming 150 pg of total protein per cell.60
b
Cells are treated with all‐trans retinoid acid.
c
Study did not specify that TSP data are limited to TSP‐1.
d
Cells are treated with ATP and prostaglandin E2, respectively. Values are rounded to the nearest integer.