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. 2018 Jan 29;22(4):2220–2230. doi: 10.1111/jcmm.13502

Figure 5.

Figure 5

Effect of two VLA‐4 inhibitors (BIO1211 and BIO5192) on cell proliferation and invasion in GIST882 (A, B), GIST48 (C, D) and GIST‐T1 (E, F) cell lines. Panels (A, C, E): VLA‐4 inhibitors had little effect on cell proliferation. Panels (B, D, F): ITGA4 inhibition with a VLA‐4 inhibitor decreased cell invasion of each cell line 24 hrs (GIST882 and GIST48) or 96 hrs (GIST‐T1) after the treatment. The bars indicate the average number of invaded cells (the standard errors per one microscope field are shown).