Table V.

Changes in the Aberrant Behavior Checklist – Community (ABC) raw scores after one year of treatment with levodopa or placebo, and the relative difference in the changes between these two groups. A positive “difference in gains” suggests that either the gain (i.e., worsening) in that behavior was greater in the levodopa group than in the control group, or the reduction (i.e., improvement) in that behavior was less in the levodopa group compared to the control group.

Aberrant Behavior Checklist Raw Score: Mean ± SD	Levodopa (n=29)			Placebo (n=26)			Difference in Gains (Levodopa - Placebo)	Difference in Gains (Generalized Estimating Equation)
	Initial	1-year	Gain in 1 year	Initial	1-year	Gain in 1 year		95% C.I.	p value
Irritability	9.1 (± 9.3)	7.3 (± 8.0)	−1.8	4.8 (± 6.0)	6.6 (± 7.1)	1.8	−3.6	(−6.85, 0.16)	0.06
Lethargy	4.7 (± 4.6)	4.5 (± 3.9)	−0.3	2.7 (± 3.3)	5.2 (± 8.4)	2.5	−2.8	(−6.37, 0.76)	0.12
Stereotypy	5.1 (± 3.7)	3.5 (± 3.7)	−1.6	3.0 (± 3.6)	3.6 (± 3.9)	0.7	−2.2	(−3.93, −0.33)	0.02
Hyperactivity	19.5 (± 12.2)	18.2 (± 9.9)	−1.3	15.5 (± 10.8)	17.0 (± 10.4)	1.5	−2.8	(−7.74, 1.66)	0.20