Table 1.
Demographic and Baseline Clinical Characteristics of Participants Enrolled in an 18-Month Randomized Trial of Cognitive Enhancement Therapy Versus Enriched Supportive Therapy for Adult Autism Spectrum Disorder.
| Variable | CET (N = 29) | EST (N = 25) | pb |
|---|---|---|---|
|
| |||
| N (%) | N (%) | ||
| Age, mean (SD) | 22.55 (6.38) | 23.60 (5.61) | .527 |
| Male | 24 (83%) | 23 (92%) | .547 |
| White | 27 (93%) | 17 (68%) | .044 |
| Attended College | 15 (52%) | 20 (80%) | .060 |
| Employed | 7 (24%) | 10 (40%) | .338 |
| Living Independentlya | 4 (14%) | 4 (17%) | 1.00 |
| IQ, mean (SD) | 108.69 (13.83) | 105.40 (15.71) | .417 |
| ADOS Score | |||
| Communication | 3.21 (1.08) | 3.52 (1.48) | .374 |
| Reciprocal Social Interaction | 6.55 (2.25) | 7.60 (2.89) | .140 |
| Stereotyped Behavior | 2.45 (1.40) | 3.08 (1.71) | .142 |
| Receiving psychiatric medicationsa | 13 (46%) | 15 (62%) | .379 |
| Antidepressants | 13 (46%) | 14 (58%) | .563 |
| Mood stabilizers | 1 (4%) | 0 (%) | - |
| Anxiolytics | 1 (4%) | 4 (17%) | .261 |
| Antipsychotics | 2 (7%) | 1 (4%) | 1.00 |
Note. ADOS = Autism Diagnostic Observation Schedule; CET = Cognitive Enhancement Therapy; EST = Enriched Supportive Therapy
a
N = 52, as 2 participants (1 in CET, 1 in EST) withdrew prior to completing pre-treatment data collection.
b
χ2 test or analysis of variance, two-tailed, for significant differences between treatment groups.
P-values are adjusted for multiplicity using Benjamini and Hochberg’s (1995) approach.