Figure 1a. Best Target Response in Patients
Waterfall plot depicting best target response in all patients on study. Seven patients had a response and 8 patients had stable disease. Individuals with BRCA mutations overwhelmingly had a response compared to those without mutations. The patient with unknown BRCA status had a 21.4% reduction per RECIST 1.1.
Figure 1b. Overall Survival and Treatment Duration
Swimmers plot depicting overall survival and indicating treatment duration. Note that BRCA+ patients remained on treatment for a longer duration and had more favorable survival. The patient with unknown BRCA status was on treatment for 8.8 months and had an OS of 12.3 months.