TABLE 1.
Characteristics, n (%) | No prior disease N=2,198 |
With prior disease N=162 |
P-value | ||
---|---|---|---|---|---|
Female | 1,061 | (48) | 42 | (26) | <.001 |
White, non-Hispanic | 1,959 | (89) | 145 | (90) | .88 |
Median age at HCT (range), years | 43.6 | (0.4–78.8) | 48.9 | (10.0–78.9) | <.001 |
Median age at cohort entry (range), years | 55.5 | (20.2–83.3) | 62.4 | (22.0–83.0) | <.001 |
Original disease | .25 | ||||
Leukemia / myelodysplastic syndrome | 1,265 | (58) | 102 | (63) | |
Lymphoma | 481 | (22) | 26 | (16) | |
Multiple myeloma | 234 | (11) | 19 | (12) | |
Other cancer | 60 | (3) | 1 | (1) | |
Non-malignant condition | 158 | (7) | 14 | (9) | |
Donor type | .42 | ||||
Autologous | 635 | (29) | 42 | (26) | |
Allogeneic | 1,563 | (71) | 120 | (74) | |
History of chronic graft vs. host disease | 967 | (62)* | 95 | (79)* | <.001 |
Body mass index categories, kg/m2 | .046 | ||||
<18.5 | 66 | (3) | 2 | (1) | |
18.5–24.9 | 945 | (44) | 55 | (34) | |
25–29.9 | 744 | (34) | 67 | (42) | |
≥30 | 411 | (19) | 36 | (23) | |
Hypertension | 568 | (26) | 90 | (56) | <.001 |
Dyslipidemia | 673 | (31) | 126 | (78) | <.001 |
Diabetes | 281 | (13) | 55 | (34) | <.001 |
Current smoker | 157 | (8) | 17 | (10) | .18 |
Fruit/vegetable intake | |||||
No. servings/day, median (interquartile range) | 3.4 | (2.1–5.2) | 3.2 | (2.0–4.6) | .23 |
≥5 servings/day | 509 | (28) | 29 | (22) | .11 |
Physical activity, minutes/week† | .023 | ||||
<90 | 611 | (38) | 59 | (48) | |
90–239 | 511 | (31) | 40 | (32) | |
≥240 | 504 | (31) | 25 | (20) | |
Met national activity recommendations‡ | 1,079 | (66) | 67 | (54) | .005 |
Died during follow-up period | 277 | (13) | 39 | (24) | <.001 |
Among allogeneic recipients.
In terms of vigorous physical activity; comparable time spent doing moderate activity was divided by two.
150 minutes of moderate activity per week or 75 minutes of vigorous activity per week, or equivalent mixture of both