Figure 7. Electrospun nanofibers for engineering 3D cancer models.

Effect of flow perfusion on ewing sarcoma cell morphology and distribution in a 3D electrospun PCL nanofiber cancer model. (A) SEM micrographs of the surface of scaffolds for the different flow. Scale bar is equivalent to 100 µm in all micrographs. (B) Fluorescence microscopy of the cross section of scaffolds. Bright field images of scaffold fibers are overlapped with ewing sarcoma cells fluorescently stained with DAPI (blue staining). (Scale bar, 200 µm) Reproduced with permission.^[101] Copyright 2015, PNAS.