. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: Adv Healthc Mater. 2017 Dec 6;7(6):e1701024. doi: 10.1002/adhm.201701024

Table 2.

Electrospun nanofiber-based biosensors for cancer cell detection.

Materials	Type of sensing	Type of interaction	Sensitivity	Refs
Multiwalled carbon nanotubes (MWCNT) embedded ZnO nanofibers	Detection of carcinoma antigen-125	Antigen/antibody interaction	90.14 µA/(U/mL)/cm²	[20]
Graphene foam modified with electrospun carbon-doped TiO₂ nanofibers	Detection of breast cancer biomarker EGFR2, ErbB2	Antigen/antibody interaction	0.585 µA/µM/cm²	[121]
PS/PSMA nanofibers	Detection of matrix metalloproteinases (MMPs)	Specific interaction between enzyme (MMPs) and substrate (peptides)	10 pM	[122]
Mesoporous zinc oxide nanofibers	Detection of breast cancer biomarker EGFR2, ErbB2	Antigen/antibody interaction	7.76 kΩ/µM; 1 fM (4.34 × 10⁻⁵ ng/mL)	[125]
PEDOT:PSS/PVA nanofibers	Detection of carcinoembryonic antigen	Antigen/antibody interaction	14.2 µA/ng mL/cm²	[102]
PVA/PAA nanofibers	Detection of pH changes	pH response	74 mV/pH	[123]
Core/shell fibers with PCL as shell and Ru(dpp) and PtOEP containing PDMS as the core	Oxygen detection	Oxygen response	Response less than 0.5 s	[124]