Table 2. Differences in levels of complement components in ADEs and NDEs.
ADEs | C5b-C9 TCC | C3d | C4b | Bb | Factor B | Factor D | ||||||
Subjects | Cntrl | AD | Cntrl | AD | Cntrl | AD | Cntrl | AD | Cntrl | AD | Cntrl | AD |
355 | 1212 | 48,705 | 416,093 | 64,305 | 166,151 | 91,933 | 252,271 | 113,321 | 547,292 | 1465 | 5800 | |
NDEs | C5b-C9 TCC | C3d | C4b | Bb | Factor B | Factor D | ||||||
Subjects | Cntrl | AD | Cntrl | AD | Cntrl | AD | Cntrl | AD | Cntrl | AD | Cntrl | AD |
54.2 | 68.8 | 1855 | 11,562 | 3851 | 9354 | 6059 | 14,624 | 2055 | 7128 | 94.2 | 306 |
Cntrl= controls and AD= Alzheimer's disease patients. All values shown are mean pg/ml (values for mean±S.E.M. are in the text of Results or in the legend for Figure 2). All differences between levels of corresponding analytes in ADEs and NDEs are significant with p<0.0001.