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(A,B) CMO induces antiproliferative effect in time- and dose-dependent manner. HepG2 and HCCLM3 cells were plated in triplicate, treated with indicated concentrations of CMO, and then subjected to MTT assay after 24, 48, and 72 h to analyze proliferation of cells. The data are expressed as mean ± SD, compared with the untreated control (*p < 0.05, **p < 0.01).
