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. 2017 Jul 20;102(3):388–392. doi: 10.1136/bjophthalmol-2017-310268

Table 1.

Characteristics of the phenotypes from cluster analysis

Phenotype
Characteristics 1 (n=16, 20.8%) 2 (n=52, 67.5%) 3 (n=9, 11.7%) p Value
Soft drusen 56.3 (29.9 to 80.2) 34.6 (22.0 to 49.1) 0.0 (0 to 33.6) 0.013
RPD 50.0 (24.7 to 75.3) 80.8 (67.5 to 90.4) 100 (66.4 to 100) 0.012
Foveal atrophy 100 (79.4 to 100) 0.00 (0 to 6.8) 0.00 (0 to 33.6) <0.001
High FAF 12.5 (1.6 to 38.3) 73.1 (59.0 to 84.4) 88.9 (51.8 to 99.7) <0.001
Greyish FAF appearance 0.0 (0 to 20.6) 0.0 (0 to 6.8) 100 (66.4 to 100) <0.001
SFCT (µm) 197 (118 to 253) 134 (82 to 179) 51 (26 to 60) 0.0001
Area growth rate (mm2/year) 0.63 (0.32 to 1.32) 1.91 (1.27 to 2.59) 1.73 (1.24 to 2.06) 0.0005
Linear growth rate (mm/year) 0.17 (0.09 to 0.32) 0.33 (0.20 to 0.43) 0.32 (0.24 to 0.42) 0.022

Results are shown as percentage (95% CI) for categorical variables and median (25th and 75th percentiles) for quantitative variables. The p value corresponds to the comparison between the three groups.

FAF, fundus autofluorescence; RPD, high reticular pseudodrusen load; SFCT, subfoveal choroidal thickness.