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IL-27 reduces IL-27Rα and induces IDO and A3G expression in uterine stromal fibroblasts. Confluent monolayers of fibroblasts were treated with recombinant human IL-27 for 24 h before mRNA recovery and analysis for IL-27Rα (A), gp130 (B), IDO (C), APOBEC3G (A3G) (D), MxA (E), OAS2 (F), and TLR3 (G) by RT-PCR. *P < 0.05. APOBEC3G, apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G; IDO, indoleamine 2,3-dioxygenase.
