Figure 11.
Survival of M. tb in THP-1 cells. THP-1 cells were cultured in a medium of RPMI and 10% FBS, and allowed to differentiate into macrophages by addition of PMA at a concentration of 10 ng/mL. M. tb-infected macrophages (2 × 105/well) were either untreated or treated with L-GSH (40 μM). There was a significant reduction in M. tb numbers when THP-1 cells were treated with L-GSH. Data represent means ± SE from six trials, plating each multiple times. ** p < 0.005 when comparing L-GSH treated samples to untreated samples at 12 days.