Figure 1.

Amiloride improved motor function recovery after spinal cord injury (SCI). Basso, Beattie, Breanahan locomotor rating scale (BBB) scale scores were significantly higher in the amiloride group compared to the phosphate buffered saline (PBS) group from day 21 to day 56. Asterisks indicate significant difference between the amiloride group (Ami) and the PBS group (PBS) with two-way repeated measures analysis of variance (ANOVA), followed by Tukey’s multiple comparison test (* p < 0.05, ** p < 0.01, n = 5 per group, error bars are standard deviations).