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Obese larvae show activation of JNK/SAPK signaling and increased ROS production. (a) Western blot from lysates of FBs showing the level of phosphorylation of JNK/SAPN p46 kinase, in P0206-Gal4 (control) and P0206-Gal4; UAS-Ni animals. Actin was used as control loading. (b) Confocal photographs (20x) of cells from FBs stained with DHE (red) for ROS and Hoechst (blue) for nuclei.
