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. 2017 Nov 8;314(2):R265–R273. doi: 10.1152/ajpregu.00147.2017

Fig. 7.

Fig. 7.

Effect of systemic IL-17 blockade on infiltrating pulmonary immune cells and lung structure after recovery from renal ischemia-reperfusion (I/R). Representative hematoxylin and eosin (H&E)-stained (A) and picrosirius red-stained sections (C) through rat lung are shown from I/R+vehicle and I/R+IL17Rc-treated rats; Bar = 100 µm. Quantification of cell density based in H&E-stained sections (B) and fibrosis based on picrosirius red staining (D) is shown. E: frequency of CD4 and CD8 cells in bronchoalveolar lavage (BAL) fluid; F: frequency of CD4+IL-17+ and CD8+IL-17+. Data are means ± SE. *P < 0.05 I/R vehicle vs. IL17RC by Student’s t-test. n = 5–7 per group.