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. 2018 Mar 13;9(3):159. doi: 10.3390/genes9030159

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Schematic representation of the mechanisms of action of CD99wt and CD99sh in tumor cells. The two isoforms exhibit opposite effects on cell migration, inhibiting or activating the Src signaling pathway [18,21,53].