Fig. 3. 2D IR spectra of L16V17 (a–d), V17 (e–h), L12A13 (i–l) and A13 (m–p) peptides taken at different aggregation times. The time-dependent diagonal intensity slices through the overtone band at different aggregation times are plotted on the right. The most complex intensity changes were observed for the L12A13 hIAPP suggesting that more than two distinct structures are formed during the aggregation process.
