Table 5.
Univariate and multivariate analysis of factors associated with BALF positivity in pulmonary TB sputum-negative suspects and those without sputum
| Total | BALF (+) | BALF (−) | P-value | OR (95% CI)a | |
|---|---|---|---|---|---|
| n = 285 (%) | n = 743 (%) | ||||
| Age (year) | < 0.001 | ||||
| ≤ 25 | 244 | 105 (43.0) | 139 (57.0) | Reference | |
| 25–35 | 288 | 88 (30.6) | 200 (69.4) | 0.582 (0.408–0.832) | |
| 35–45 | 215 | 44 (20.5) | 171 (79.5) | 0.341 (0.224–0.517) | |
| 45–55 | 128 | 22 (17.2) | 116 (82.8) | 0.251 (0.149–0.423) | |
| 55–65 | 106 | 23 (21.7) | 83 (78.3) | 0.367 (0.217–0.621) | |
| > 65 | 37 | 3 (8.1) | 34 (91.9) | 0.117 (0.035–0.391) | |
| Cavity | < 0.001 | ||||
| No | 924 | 228 (24.7) | 696 (75.3) | Reference | |
| Yes | 104 | 57 (54.8) | 47 (45.2) | 4.108 (2.376–7.102) | |
| IGRA | < 0.001 | ||||
| Negative | 431 | 64 (14.8) | 367 (85.2) | Reference | |
| Positive | 507 | 201 (39.6) | 306 (60.4) | 3.743 (2.478–5.655) | |
| CD8+ | 0.002 | ||||
| > 500 | 205 | 46 (22.5) | 159 (77.5) | Reference | |
| ≤ 500 | 468 | 153 (32.7) | 315 (67.3) | 1.992 (1.289–3.076) |
TB tuberculosis, BALF bronchoalveolar lavage fluid, NAAT nucleic acid amplification test, IGRA interferon-γ release assays
aControlling for variables with P < 0.05 in univariate analysis