Table 3.

Results From the JAG Test in AAs

Gene	No. of SNPs	No. of effective SNPsa	COPDGene Pemp	SAGE Pemp	MESA Pemp	Combined Pemp	FDR corrected P
CPD
CHRNA9	247	12b	.005	.321	.424	.004	.193
PICK1	29	4c	.067	.082	.043	.040	.729
NTRK2	443	19d	.031	.824	.667	.048	.782
DLG4	7	2	.080	.458	.841	.083	.782
CAMK2B	50	3e	.092	.504	.877	.098	.799
FTND
IQGAP1	400	7	.020	.016	NA	.005	.193
PDIA3	120	5	.011	.701	NA	.021	.556
UNC50	56	2	.019	.649	NA	.031	.653
UBXN2A	271	5	.012	.918	NA	.040	.729
EPHA4	221	10	.028	.791	NA	.055	.782
NLGN1	1668	36	.062	.493	NA	.070	.782
NCAM1	427	10f	.106	.170	NA	.071	.782
FYN	635	15	.085	.406	NA	.084	.782
PPP3CA	408	12	.068	.607	NA	.089	.799
LAMB1	187	10	.156	.111	NA	.093	.799
CACNA2D1	1325	40g	.077	.567	NA	.094	.799

The P-value for each gene is shown for each study as well as the combined P-value for genes associated with CPD or FTND at P < .1.

^aThe number of signals tested in the gene in each study (unless otherwise noted) as calculated by JAG.

^bEleven signals in the MESA data.

^cThree signals in the MESA data.

^dEighteen signals in the MESA data.

^eTwo signals in the MESA data.

^fNine signals in the SAGE data.

^gThirty-nine signals in the SAGE data.