Table 1.
Name | Description | Group | Homology | Mol. marker | Cells and anatomical position | Known projections |
---|---|---|---|---|---|---|
PTar | Anterior PT rostral group | DC2 | A11 | otp | Large, pear-shaped, in peri-ventricular nucleus of PT | Endohypothalamic, ascending: SP descending: Rh, SC |
PTac | Anterior PT caudal group | DC4 | A11 | otp | Large, in periventricular nucleus of caudal PT | Endohypothalamic, descending: Rh, SC |
PTp | Posterior PT posterior group | DC5 | A11 | otp | Small round cells of peri-ventricular nucleus of PT | Fewer or no connections to the SC |
PTN | Posterior tuberal nucleus | DC6 | A11 | otp | Small round cells of posterior tuberal nucleus | Few or no connections to the SC |
Hdm | Dorsal medial hypothalamus | DC3 | A14 | nkx2.1 | Small round liquor contacting cells | Local, hypothalamic |
nkx2.2 | ||||||
Hc | Caudal hypothalamus | DC7 | A14 | nkx2.1 | Small cells in caudal hypothalamus | Local, hypothalamic |
Groups of DA neurons in the diencephalon named according to their anatomical location. Molecular markers suggest homology to mammalian DA groups (Ryu et al., 2007; Yamamoto and Vernier, 2011). Zebrafish DA clusters (DC) have previously been numbered from rostral to caudal (Rink and Wullimann, 2001). Far projecting neurons send descending projections into the rhombencephalon, spinal cord and to peripheral sensory organs. nkx 2.1, NK2 homeobox 1 transcription factor; otp, Orthopedia transcription factor; PT, posterior tuberculum; Rh, rhombencephalon; SC, spinal cord; SP, subpallium.