Skip to main content
. 2018 Mar 19;12:20. doi: 10.3389/fnana.2018.00020

Table 1.

Ventral diencephalic dopaminergic clusters (Introduction).

Name Description Group Homology Mol. marker Cells and anatomical position Known projections
PTar Anterior PT rostral group DC2 A11 otp Large, pear-shaped, in peri-ventricular nucleus of PT Endohypothalamic, ascending: SP descending: Rh, SC
PTac Anterior PT caudal group DC4 A11 otp Large, in periventricular nucleus of caudal PT Endohypothalamic, descending: Rh, SC
PTp Posterior PT posterior group DC5 A11 otp Small round cells of peri-ventricular nucleus of PT Fewer or no connections to the SC
PTN Posterior tuberal nucleus DC6 A11 otp Small round cells of posterior tuberal nucleus Few or no connections to the SC
Hdm Dorsal medial hypothalamus DC3 A14 nkx2.1 Small round liquor contacting cells Local, hypothalamic
nkx2.2
Hc Caudal hypothalamus DC7 A14 nkx2.1 Small cells in caudal hypothalamus Local, hypothalamic

Groups of DA neurons in the diencephalon named according to their anatomical location. Molecular markers suggest homology to mammalian DA groups (Ryu et al., 2007; Yamamoto and Vernier, 2011). Zebrafish DA clusters (DC) have previously been numbered from rostral to caudal (Rink and Wullimann, 2001). Far projecting neurons send descending projections into the rhombencephalon, spinal cord and to peripheral sensory organs. nkx 2.1, NK2 homeobox 1 transcription factor; otp, Orthopedia transcription factor; PT, posterior tuberculum; Rh, rhombencephalon; SC, spinal cord; SP, subpallium.