Table 1.

Semi-quantitative analysis of the amount of nuclear nuclear factor interleukin 6 (NF-IL6) signals in the paraventricular nucleus (PVN) and the median eminence (ME) of young and old male rats 24 h after injection of LPS (100 μg/kg) or PBS.

Brain structure	Nuclear NF-IL6 immunoreactivity
	PBS young	LPS young	PBS old	LPS old
PVN	− (1,25)	± (2,4)	− (1,17)	± (2,2)
ME	− (1,4)	+ (2,8)	− (1,4)	++ (4)

A five-point scale was used to rate the data: − (1) no signals, ± (2) single signals in some cases, + (3) low density; ++ (4) moderate density, +++ (5) high density; n = 3-6 animals per group, 2 sections per animal; the robust difference between young and old is highlighted in bold.