Table 2.
Characteristics of the 15 patients with brain metastasis from ESCC.
| Characteristic | No. of patients (%) |
|---|---|
| Age at diagnosis of primary ESCC | |
| Median (range) | 60 (43-73) years |
| Gender | |
| Male | 14 |
| Female | 1 |
| Treatment of primary tumor | |
| Surgery with or without chemo/radiotherapy | 4 |
| Chemoradiotherapy | 11 |
| Time from diagnosis of primary ESCC to brain metastases | |
| Median (range) | 13 (0-47) months |
| No treatment | 0 |
| Neurological symptoms of brain metastases | |
| Dizziness/headaches | 15 |
| Limb weakness | 6 |
| Seizures | 3 |
| Visual-field defects | 2 |
| Systemic metastases | |
| Yes | 9 |
| Diagnosed before brain metastases | 3 |
| Diagnosed after brain metastases | 6 |
| KPS at diagnosis of brain metastases | |
| 90 | 9 |
| 80 | 5 |
| ≤ 70 | 1 |
| No. of brain metastases | |
| 1 | 10 |
| 2-3 | 4 |
| > 3 | 1 |
| Diameter of all brain lesions | |
| Median (range) | 4.6 (0.8-8.0)cm |
| Maximum diameter ≥ 3.0 cm | 11 |
| Maximum diameter < 3.0 cm | 4 |
| GPA score | |
| 0-2.0 | 4 |
| 2.5-3.0 | 11 |
| Histology of brain lesions | 8 |
| Poorly differentiated squamous carcinoma | 6 |
| Well-differentiated squamous carcinoma | 1 |
| Grade unknown | 1 |