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Autophagy induced by co-treatment with BEZ235 and TSA in ESCC cells. A Co-treatment of BEZ235 (150 nM) and TSA (450 nM) for 48 hours, significantly increased the expression of both LC3-II and Beclin-1. Percentage of autophagic proteins expression of Eca-109 (B) and TE-1 (C) cell, compared to control. *p<0.05 compared with control and single reagent.
