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. 2018 Feb 28;9(6):987–997. doi: 10.7150/jca.22861

Table 2.

Associations of beclin-1 and LC3 expressions with chinicopathologic characteristics in ESCCs.

Factors No Beclin-1 p
LC3 p
n (+) n(-) n(+) n(-)
Age
≤65 83 50 33 0.381 37 46 0.216
>65 35 18 17 20 15
Sex
Male 98 54 44 0.223 49 49 0.419
Female 20 14 6 8 12
Tumor location
Upper 17 11 6 0.520 8 9 0.434
Middle 68 39 29 36 32
Lower 33 18 15 13 20
Surgical type
2-FL 60 37 23 0.371 31 29 0.462
3-FL 58 31 27 16 32
Differentiation
Well 8 4 4 0.226 7 1 0.750
Moderately 73 47 26 28 45
Poorly 37 17 20 22 15
T stage
T1+ T2 60 39 21 0.101 37 23 0.003
T3+T4 58 29 29 20 38
TNM stage
I 22 17 5 0.006 17 5 0.000
II 48 30 18 28 20
III 37 15 22 8 29
IV 11 6 5 4 7
Comorbidities
Highblood 60 27 33 0.004 28 32 0.720
Copd 13 9 4 0.374 8 5 0.316
Cardiovascular disease 19 11 8 0.980 12 7 0.160
Arrhythmia 11 6 5 0.830 4 7 0.410
Diabetes 40 23 17 0.984 17 23 0.370
Complications
90-day mortality 4 1 3 0.017 2 2 0.946
Fistula 13 4 9 0.038 5 8 0.456
Sepsis 11 4 7 0.136 6 5 0.667
Pneumonia 56 32 24 0.920 30 26 0.281
cardiac insufficiency 21 12 9 0.961 9 12 0.585
mTOR
Positive 62 28 34 0.005 25 37 0.097
Negative 56 40 16 32 24
LC3
Positive 57 35 22 0.427
Negative 61 33 28