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. 2018 Feb 28;9(6):1017–1024. doi: 10.7150/jca.23087

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LASS2 regulates mitochondrial dynamics and membrane potential in bladder cancer cells. A. Flow cytometry/JC-1 staining showed that in J82 and BIU87, LASS2 transfection downregulated the percentage of red fluorescence. In 5637 cells, LASS2 siRNA upregulated the percentage of red fluorescence. B. Mitrotracker Red staining showed that LASS2 transfection increase the level of mitochondria length (fusion) in J82 and BIU87 cells. While in 5637 cells LASS2 depletion decreased mitochondria length (fission). *: p<0.05.