Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 30;67(4):736–745. doi: 10.1136/gutjnl-2016-312577

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

PMC Copyright notice

H3L3 pan-genotypically inhibits HCVpp entry into primary human hepatocytes (PHH) without escape. PHH from a panel of donors were treated with serial dilutions of H3L3 (0.001 μg/mL to 100 μg/mL) for 1 hour at 37°C prior to incubation with pseudoparticles bearing glycoproteins of all major genotypes of HCV. HCVpp entry was assessed by measuring luciferase activity after 72 hours. Entry is expressed as a percentage relative to entry into untreated cells. Graphs show one experiment performed in duplicate.