Skip to main content
. 2018 Feb 2;293(12):4324–4333. doi: 10.1074/jbc.RA117.001573

Table 3.

Predicted cancer-associated amino acid mutations in IGF2

#fs indicates frameshift.

Mutation Population variant ExAC prevalence
M5I M5R 1 allele
S20I S20L, S20W 11 alleles, 1 allele
A24T None
A25V None
R27H None
G35R None
F43L None
R48H R48L 1 allele
Y52stop None
S53R None
R61H R61H 1 allele
R64C, R64H R64C 1 allele
V67I None
R73C, R73H None
E91K None
S95L None
P98L P98L, P98Q 1 allele, 1 allele
P102L P102L 6 alleles
F114L None
R127C, R127H, R127S None
G129S None
L133V None
#R137Afs*22 None
K153I None
H155D None
L161V None
T163L None
D165Y D165E 1 allele
#G170Afs*30 G170D, G170S 2 alleles, 1 allele
A171T A171V 1 allele
#P173Qfs*27 P173A, P173Q, P173R, P173S 4 alleles, 1 allele 4 alleles, 3 alleles
#E174Rfs*50 E174D 1 allele