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. 2017 Nov 4;67(2):226–236. doi: 10.1136/gutjnl-2017-314205

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This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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The gastric carcinoma microbiota is characterised by nitrosating bacteria. Functional classification of the predicted metagenome content of the microbiota of chronic gastritis and gastric carcinoma using (A) COG and (B) KO. The normalised relative frequency of nitrate reductase and nitrite reductase in patients with chronic gastritis and gastric carcinoma is shown. Significance was considered for adjusted P<0.05. COG, Clusters of Orthologous Groups; KO, Kyoto Encyclopedia of Genes and Genome (KEGG) orthology; NADH, nicotinamide adenine dinucleotide; NO, nitric oxide; TMAO, trimethylamine N-oxide.