Table 5. Comparison of Di-Ubiquitin Linkage Preferences of Various USPs.
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---|---|---|---|---|---|---|---|---|
Lys6 | Lys11 | Lys27 | Lys29 | Lys33 | Lys48 | Lys63 | Linear | |
USP1 (21-785) | +++ | ++ | + | + | ++ | +++ | +++ | - |
USP7 | +++ | +++ | ++ | + | ++ | +++ | +++ | - |
USP8CD | +++ | +++ | +++ | +++ | +++ | +++ | +++ | - |
USP11 | +++ | +++ | +++ | ++ | +++ | +++ | +++ | - |
USP16 | ++ | +++ | +++ | +++ | +++ | +++ | +++ | + |
aUSP17 | ++ | +++ | + | + | +++ | +++ | +++ | - |
Evaluation of chain linkage preferences was obtained from Faesen et al (18).
values are reported from this paper