Table 1.
Summary of the case data for human postmortem brain immunohistochemistry analysis.
| Case | PVL/control | GA at birth (weeks) | Postnatal age | Case details | IHC staining: periventricular white matter | IHC staining: meninges |
|---|---|---|---|---|---|---|
| 1 | Control | 23 + 6/7 | 9 h 51 min | No brain pathology observed. Male, 545 g Sepsis, cefotaxime treatment |
CD3: – CD20: – |
CD3: – CD20: – |
| 2 | Control | 27 + 5/7 | <1 day | No brain pathology observed. Female, 886.4 g Atrioventricular septal defect |
CD3: ± CD20: – |
CD3: ± CD20: – |
| 3 | Control | 28 + 1/7 | <1 day | No brain pathology observed. Male, 1308.4 g No infection, no antibiotics |
CD3: ± CD20: ± |
CD3: ± CD20: ± |
| 4 | PVL | 26 + 5/7 | 1 day 7 h | PVWMI. Male. 641.4 g Oligohydramnios, maternal hypertension |
CD3: + CD20: + |
CD3: ++ CD20: + |
| 5 | PVL | 26 + 6/7 | 2 days | PVWMI. Male, 807.6 g Patent ductus arteriosus |
CD3: + CD20: + |
CD3: ++ CD20: + |
| 6 | PVL | 24 + 6/7 | 16 days 19 h | PVWMI. Male, 715.4 g Rupture of membranes; oligohydramnios, AFI |
CD3: + CD20: + |
CD3: + CD20: + |
−: no positive cells; ±: positive cells seen inside the blood vessels; +: positive cells seen; + +: positive cells easily seen.
GA, gestational age; PVL, periventricular leukomalacia; PVWMI, periventricular white-matter injury; AFI, amniotic fluid infection.