Table 3.
Gram-negative isolates resistance or intermediate-susceptibility to tested antimicrobials
| Overall | Benin | Congo | Liberia | Madagascar | Sierra Leone | Togo | P value | |
| Enterobacteriaceae | 662 | 162 | 98 | 87 | 141 | 83 | 91 | |
| Ampicillin | 496 (74.9) | 146 (90.1) | 83 (84.7) | 35 (40.2) | 100 (70.9) | 65 (78.3) | 67 (73.6) | <0.001 |
| Gentamicin | 172 (26.0) | 50 (30.9) | 26 (26.5) | 33 (37.9) | 26 (18.4) | 20 (24.1) | 17 (18.7) | 0.009 |
| Ceftriaxone | 162 (24.5) | 58 (35.8) | 25 (25.5) | 24 (27.6) | 23 (16.3) | 19 (22.9) | 13 (14.3) | 0.001 |
| Ciprofloxacin | 141 (21.3) | 47 (29.0) | 25 (25.5) | 22 (25.3) | 20 (14.2) | 17 (20.5) | 10 (11.0) | 0.003 |
| TMP/SMX | 406 (61.3) | 111 (68.5) | 57 (58.2) | 62 (71.3) | 77 (54.6) | 52 (62.7) | 47 (51.6) | 0.016 |
| Imipenem | 15 (2.3) | 1 (0.6) | 1 (1.0) | 2 (2.3) | 1 (0.7) | 4 (4.8) | 6 (6.6) | 0.013 |
| Amp+Gent | 146 (22.1) | 50 (30.9) | 26 (26.5) | 11 (12.6) | 25 (17.7) | 19 (22.9) | 15 (16.5) | 0.006 |
| Quin+Ceph3 | 102 (15.4) | 41 (25.3) | 16 (16.3) | 14 (16.1) | 12 (8.5) | 11 (13.3) | 8 (8.8) | 0.001 |
| Resistant to ≥2 classes* | 159 (24.0) | 54 (33.3) | 21 (21.4) | 27 (31.0) | 24 (17.0) | 21 (25.3) | 12 (13.2) | 0.001 |
| Resistant to ≥3 classes* | 85 (12.8) | 32 (19.8) | 15 (15.3) | 11 (12.6) | 10 (7.1) | 8 (9.6) | 9 (9.9) | 0.023 |
| Resistant to ≥4 classes* | 2 (0.3) | 0 (0.0) | 0 (0.0) | 1 (1.1) | 0 (0.0) | 0 (0.0) | 1 (1.1) | 0.363 |
| Pseudomonas spp | 287 | 63 | 52 | 42 | 41 | 30 | 59 | |
| Gentamicin | 67 (23.3) | 10 (15.9) | 10 (19.2) | 11 (26.2) | 15 (36.6) | 4 (13.3) | 17 (28.8) | 0.097 |
| Ciprofloxacin | 48 (16.7) | 11 (17.5) | 6 (11.5) | 7 (16.7) | 9 (22.0) | 4 (13.3) | 11 (18.6) | 0.816 |
| Imipenem | 19 (6.6) | 1 (1.6) | 4 (7.7) | 3 (7.1) | 3 (7.3) | 2 (6.7) | 6 (10.2) | 0.559 |
| Acinetobacter spp | 102 | 26 | 15 | 14 | 22 | 17 | 8 | |
| Gentamicin | 26 (25.5) | 8 (30.8) | 5 (33.3) | 5 (35.7) | 4 (18.2) | 1 (5.9) | 3 (37.5) | 0.278 |
| Ciprofloxacin | 27 (26.5) | 10 (38.5) | 3 (20.0) | 2 (14.3) | 2 (9.1) | 7 (41.2) | 3 (37.5) | 0.105 |
| TMP/SMX | 60 (58.8) | 14 (53.8) | 8 (53.3) | 10 (71.4) | 12 (54.5) | 11 (64.7) | 5 (62.5) | 0.873 |
| Imipenem | 2 (2.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (9.1) | 0 (0.0) | 0 (0.0) | 0.191 |
Presented as number (%).
P values from the Fisher exact test.
*Antimicrobial classes defined as third-generation cephalosporins, aminoglycosides, fluoroquinolones and carbapenems.
Amp+Gent, Ampicillin + Gentamicin; Quin+Ceph3, Quinolone + third-generation cephalosporin; TMP/SMX, trimethoprim/sulfamethoxazole.