Figure 1.
Inflammasome proteins are elevated in the serum of MS patients. Protein levels in pg/ml of caspase-1 (A), apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) (B), IL-1β (C), and IL-18 (D) in serum samples from patients with MS and healthy donors. p-value of significance is shown above each box plot. Box and whiskers are shown for the 5th and 95th percentile. Caspase-1: N = 9 control and 19 MS; ASC: N = 115 control and 32 MS; IL-1β: N = 21 control and 8 MS; and IL-18: N = 119 control and 32 MS.