Table 3.
Yv, OEF, CBF, CMRO2, brain volume and TMS in PWML group and control group.
| Parameter | Infants in PWML group (n = 23) | Infants in control group (n = 28) | Z | Significance (P-value) |
|---|---|---|---|---|
| Yv (%) | 68.70 (16.30, 48.00–86.00) | 63.85 (4.80, 43.00–77.00) | 2.53 | 0.012* |
| OEF (%) | 27.53 (18.94, 8.00–50.00) | 32.35 (6.26, 20.00–55.00) | −2.38 | 0.018* |
| CBF (mL/100 g/min) | 12.63 (7.83, 7.35–70.46) | 15.35 (9.13, 10.31–55.75) | −2.22 | 0.027* |
| CMRO2 (μmol/100 g/min) | 29.11 (16.80, 15.49–75.94) | 38.09 (18.84, 20.15–144.25) | −2.333 | 0.020* |
| Brain volumes (mL) | 280.35 (48.80, 229.90–366.49) | 276.84 (84.82, 134.91–435.91) | 0.25 | 0.806 |
| TMS | 9.00 (2.50, 6.00–16.00) | 11.00 (5.00, 5.50–16.00) | −2.53 | 0.011* |
| M scores | 2.00 (0.00, 2.00–6.00) | 3.00 (4.00, 1.50–6.00) | −3.62 | < 0.001* |
| C scores | 3.00 (1.00, 2.00–5.00) | 4.00 (1.75, 2.00–5.50) | −2.40 | 0.016* |
| G scores | 2.00 (1.00, 1.00–4.00) | 2.00 (0.88, 1.00–3.50) | −1.34 | 0.179 |
| B scores | 2.00 (1.00, 1.00–4.00) | 1.00 (0.75, 1.00–3.00) | 2.37 | 0.018* |
Parameter values are reported as median (interquartile range, the total range) across subjects. P-values are based on Wilcoxon two-sample exact tests. CBF, cerebral blood flow; Ya, arterial oxygen saturation; Yv, venous oxygen saturation; OEF, oxygen extraction fraction; CMRO2, cerebral metabolic rate of oxygen; TMS, total maturation score; M, Myelination; C, Cortical folding; G, Glial cell migration bands; B, Bands of migrating glial cells.
*
P < 0.05.