Table 4.
Comparison of the arterial oxygenation (Ya), venous oxygenation (Yv), oxygen extraction fraction (OEF), cerebral blood flow (CBF), and cerebral metabolic rate of oxygen (CMRO2) obtained from this study with that of previous reports.
| Study | Method | Number of subjects and condition | PMA (weeks) | Ya (%) | Yv (%) | OEF (%) | CBF (mL/100 g/min) | CMRO2 (μmol/100 g/min) |
|---|---|---|---|---|---|---|---|---|
| Altman | PET | 10 HIE, RDS, ECMO | 35.1 ± 6.2 | – | 21.6 ± 21.0 | 16.6 ± 13.2 | 21.6 ± 21.1 | 21.4 ± 16.4 |
| De vis | MRI | 10 PMA at term 9 HIE | 39 38 | 97 ± 1 96 ± 3 | 52 ± 12 65 ± 13 | 49 ± 12 32 ± 12 | 14 ± 3 12 ± 4 | 30 ± 6 24 ± 12 |
| Liu | MRI | 10 healthy | 37.4 ± 2.6 | 95.8 ± 2.2 | 62.6 ± 8.3 | 33.3 ± 2.7 | 13.4 ± 4.2 | 38.3 ± 17.7 |
| This study | MRI | 28 healthy 23 PWML | 35.71 (5.36) 35.14 (3.29) | 95 (2) 95 (2) | 63.85 (4.80) 68.70 (16.30) | 32.35 (6.26) 27.53 (18.94) | 15.35 (9.13) 12.63 (7.83) | 38.09 (18.84) 29.11 (16.80) |
| Elwell | NIRS | 9 ventilatory support | 29.2 ± 5.3 | – | – | – | – | 45.9 ± 12.3 |
| Skov | NIRS | 10 asphyxiated (term) 22 RDS (preterm) | 38.8 ± 1.4 29.8 ± 2.6 | 94 ± 7 96.5 ± 5 | 67.3 ± 9.4 53.4 ± 15.4 | 28.4 ± 0.3 44.6 ± 2.1 | 26.5 ± 17.9 11.9 ± 5.2 | 62.6 ± 35.8 44.7 ± 17.9 |
Parameter values are reported as median (interquartile range) in this study and mean ± SD in previous reports. PMA, postmenstrual age at MRI scan; HIE, Hypoxic ischemic encephalopathy; RDS, Respiratory distress syndrome; ECMO, Extracorporealmembrane oxygenation.