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. 2018 Mar;59(3):486–493. doi: 10.2967/jnumed.117.191221

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© 2018 by the Society of Nuclear Medicine and Molecular Imaging.

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FIGURE 5. — Near-infrared fluorescence imaging of PSMA expression in subcutaneous melanoma and lung xenografts with YC-27. (A) Male NOD/SCID mice bearing melanoma and lung xenografts were administered 1 nmol of a near-infrared–labeled PSMA-targeting reagent, YC-27, via tail vein injection, and fluorescence images were acquired 24 h afterward. (B) After near-infrared imaging, selected tissues were harvested and fluorescence intensity was measured and normalized to muscle fluorescence intensity. Arrow = tumor; H = heart; K = kidney; L = liver; Ms = muscle; Sp = spleen; St = stomach.