TABLE 2.

EFS and OS by CS at Diagnosis and After Induction, and Percentage Reduction in CS

CS	n	5-y EFS ± SE (%)	EFS P	5-y OS ± SE (%)	OS P
At diagnosis
≤12	126 (37%)	43.0 ± 5.7		53.9 ± 5.6
12	219 (63%)	21.4 ± 3.6	<0.001	32.7 ± 4.0	0.001
After induction
≤2	198 (60%)	39.2 ± 4.7		48.0 ± 4.7
2	132 (40%)	16.4 ± 4.2	<0.001	29.5 ± 5.1	<0.001
Reduction
≥50%	251 (76%)	31.8 ± 3.9		40.6 ± 4.0
50%	78 (24%)	25.3 ± 6.9	0.65	41.6 ± 7.5	0.91
≥75%	204 (62%)	32.3 ± 4.4		41.2 ± 4.5
75%	125 (38%)	26.9 ± 5.3	0.18	40.2 ± 5.8	0.39