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. 2017 Sep 19;23(4):952–962. doi: 10.1038/mp.2017.166

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Copyright © 2018 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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ZNF804A interacts with genes involved in translation and cell adhesion. (a) Biological processes of ZNF804A-interacting proteins. Black lines indicate new interactions identified here. Green lines indicate interactions reported by NCBI. Purple cluster represents genes in translational control. Blue cluster includes genes involved in cell adhesion and cytoskeleton. (b) Gene Ontology analysis shows enrichment of genes involved in translational regulation. (c–h) Immunoprecipitation studies confirm that ZNF804A associates with APEX1, FEZ1, LGALS1, PDHB, PDZD4 and RPSA. Each experiment has been repeated twice to confirm the results. (i) ZFP804A (red) is co-localized with GM130 (green) in CAD cells. Scale bar, 10 μm. (j) ZFP804A (red) is co-localized with endogenous RPSA (green) in CAD cells. Scale bar,10 μm.