Table III.
Parameter | I N = 24 | II N = 24 | C N = 13 | P-value |
---|---|---|---|---|
CSF CXCL9 [pg/ml] | 215 (100–346) | 166 (119–240) | 6 (5–23) | I vs. II, NS I vs. C, p < 0.001 II vs. C, p < 0.001 |
Serum CXCL9 [pg/ml] | 111 (91–137) | 138 (113–163) | 58 (51–62) | I vs. II, NS I vs. C, p < 0.001 II vs. C, p < 0.001 |
ICXCL9 | 2.0 (0.9–3.4) | 1.2 (0.9–1.6) | 0.2 (0.1–0.3) | I vs. II, p < 0.001 I vs. C, p < 0.001 II vs. C, p < 0.001 |
ICXCL9 was determined as follows: CSF CXCL9 concentration divided by serum CXCL9 concentration. Results are presented as medians and interquartile ranges. C – control group, CSF – cerebrospinal fluid, CXCL9 – monokine-induced by γ-interferon, ICXCL9 – CXCL9 index, TBE – tick-borne encephalitis.