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Immunohistochemistry for IGF-1 in CA1 region of hippocampus of different groups: A – control group (Con), B – DM group, C – sevoflurane group (Sev), D – DM + sevoflurane group (DM/Sev), E – DM + sevoflurane + celastrol group (Cel), F – expression of IGF-1 in hippocampus of rats by treatment group. N = 8 per group
*p < 0.05 as compared with control group, †p < 0.05 as compared with DM/Sev group.
