Table 9. Activation differences between adolescent and adult AN patients for emotional stimuli.
Stimulus Category | Brain region | H | Talairach coordinates | BA | Significance | ||
---|---|---|---|---|---|---|---|
x | y | z | |||||
Negative | |||||||
Adolescents>Adults | |||||||
Cerebellum | L | -27 | -71 | -15 | - | 𝑡 = 3.65, p = .0003** | |
Cerebellum | R | 31 | -53 | -19 | - | 𝑡 = 3.87, p = .0001** | |
Neutral | |||||||
Adults>Adolescents | |||||||
Cerebellum | R | 36 | -74 | -16 | - | 𝑡 = -5.00, p < .0001*** | |
Cerebellum | L | -38 | -79 | -16 | - | 𝑡 = -4.00, p < .0001** | |
Cerebellum | L | -6 | -76 | -25 | - | 𝑡 = -3.77, p = .0002** | |
Positive | |||||||
Adults>Adolescents | |||||||
Superior Parietal Lobe | L | -2 | -68 | 56 | 7 | 𝑡 = -3.65, p = .0003** | |
Superior Parietal Lobe | R | 19 | -67 | 54 | 7 | 𝑡 = -5.12, p < .0001*** | |
Superior Frontal Lobe | R | 20 | 63 | 0 | 10 | 𝑡 = -3.81, p = .0001** | |
Superior Frontal Lobe | L | -19 | 64 | 12 | 10 | 𝑡 = -4.49, p < .0001*** | |
Inferior Frontal Lobe | L | -41 | 28 | -4 | 47 | 𝑡 = -4.17, p < .0001** | |
Inferior Frontal Lobe | R | 32 | 14 | -19 | 47 | 𝑡 = -3.75, p = .0002** | |
Inferior Frontal Lobe | L | -42 | 51 | -1 | 10 | 𝑡 = -4.19, p < .0001** | |
Middle Frontal Lobe | R | 48 | 52 | 4 | 10 | 𝑡 = -4.51, p < .0001*** | |
Caudate Body | R | 7 | 17 | 14 | - | 𝑡 = -3.85, p = .0001** | |
Cerebellum | R | 36 | -74 | -16 | - | 𝑡 = -5.96, p < .0001*** | |
Cerebellum | L | -38 | -79 | -16 | - | 𝑡 = -4.12, p < .0001** | |
Cerebellum | L | -6 | -76 | -25 | - | 𝑡 = -4.10, p < .0001** |
BA = Brodman Area, H = Hemisphere. T score and p value (** = < .01, *** = < .001 after Bonferroni correction) are provided.