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. 2018 Mar 26;13(3):e0191059. doi: 10.1371/journal.pone.0191059

Table 9. Activation differences between adolescent and adult AN patients for emotional stimuli.

Stimulus Category Brain region H Talairach coordinates BA Significance
x y z
Negative
Adolescents>Adults
Cerebellum L -27 -71 -15 - 𝑡 = 3.65, p = .0003**
Cerebellum R 31 -53 -19 - 𝑡 = 3.87, p = .0001**
Neutral
Adults>Adolescents
Cerebellum R 36 -74 -16 - 𝑡 = -5.00, p < .0001***
Cerebellum L -38 -79 -16 - 𝑡 = -4.00, p < .0001**
Cerebellum L -6 -76 -25 - 𝑡 = -3.77, p = .0002**
Positive
Adults>Adolescents
Superior Parietal Lobe L -2 -68 56 7 𝑡 = -3.65, p = .0003**
Superior Parietal Lobe R 19 -67 54 7 𝑡 = -5.12, p < .0001***
Superior Frontal Lobe R 20 63 0 10 𝑡 = -3.81, p = .0001**
Superior Frontal Lobe L -19 64 12 10 𝑡 = -4.49, p < .0001***
Inferior Frontal Lobe L -41 28 -4 47 𝑡 = -4.17, p < .0001**
Inferior Frontal Lobe R 32 14 -19 47 𝑡 = -3.75, p = .0002**
Inferior Frontal Lobe L -42 51 -1 10 𝑡 = -4.19, p < .0001**
Middle Frontal Lobe R 48 52 4 10 𝑡 = -4.51, p < .0001***
Caudate Body R 7 17 14 - 𝑡 = -3.85, p = .0001**
Cerebellum R 36 -74 -16 - 𝑡 = -5.96, p < .0001***
Cerebellum L -38 -79 -16 - 𝑡 = -4.12, p < .0001**
Cerebellum L -6 -76 -25 - 𝑡 = -4.10, p < .0001**

BA = Brodman Area, H = Hemisphere. T score and p value (** = < .01, *** = < .001 after Bonferroni correction) are provided.